VIASACADEMY | IAS Online Coaching | upsc live classes

Project Dantak

Project Dantak 
According to the recent news, Project DANTAK which is perhaps the most seasoned task of the Border Roads Organization (BRO) recognized its Diamond Jubilee in Bhutan. 
More than 1,200 DANTAK faculty set out their lives while building significant framework in Bhutan. 

Main key points 
About: 
Undertaking DANTAK was set up on 24th April1961. 

It was an aftereffect of the visionary initiative of the third King of Bhutan and afterward Prime Minister of India Jawahar Lal Nehru. 

DANTAK was entrusted to build the spearheading motorable streets. 
Achievement: 

Road Connectivity: 

Throughout the long term, the Project has finished around 1600 km of blacktopped streets and 120 km of tracks in Bhutan with 5000 meters of extensions over them. 

Other Projects Executed: 

Incorporate the development of Paro Airport, Yonphula Airfield, Thimphu – Trashigang Highway, Telecommunication and Hydro Power Infrastructure, Sherubtse College, Kanglung and India House Estate. 

Medicine and Education Facilities: 
The clinical and instruction offices set up by DANTAK in distant were regularly the first in quite a while. 

Food Outlets: 

The food outlets along the street acquainted the Bhutanese with Indian luxuries and built up a sweet tooth in them. 

Indo-Bhutan Relationship: 
Indo-Bhutan Treaty of Peace and Friendship, 1949: 
The Treaty accommodates, in addition to other things, interminable harmony and companionship, deregulation and trade and equivalent equity to one another's residents. 

In 2007, the settlement was re-arranged, and arrangements were incorporated to support Bhutan's sway, nullifying the need to take India's direction on international strategy. 

Multilateral Partnership: 

The two of them share multilateral discussions like South Asian Association for Regional Cooperation (SAARC), BBIN (Bangladesh, Bhutan, India, and Nepal), BIMSTEC (Bay of Bengal Initiative for Multi Sectoral Technical and Economic Cooperation) and so on 
Economic Partnership: 
Commonly valuable hydro-power participation with Bhutan shapes the Center of reciprocal financial collaboration. 

The 720 MW Mangdechhu was appointed in August 2019. HEPs specifically, 1200 MW Punatsangchhu-I, 1020 MW Punatsangchhu-II and Kholongchhu HEP (600 MWs) are under different phases of execution. 

India is Bhutan's biggest exchanging accomplice. 
Border Roads Organization 
Brother was imagined and brought up in 1960 by Pandit Jawaharlal Nehru for organizing the expedient advancement of an organization of streets in the North and the North Eastern line districts of the country. 

It works under the managerial control of the Ministry of Defence. 
It has broadened into a huge range of development and advancement works involving runways, building projects, protection works and burrowing and has charmed itself to individuals. 

Some Recent Achievements: 

Atal Tunnel: It is situated in Himachal Pradesh's Rohtang pass. It interfaces Solang Valley close to Manali to Sissu in Lahaul and Spiti area. 

Nechiphu Tunnel: Foundation stone was laid on the Balipara-Charduar-Tawang (BCT) street in West Kameng locale of Arunachal Pradesh. 

Daporijo Bridge: It is over Subansiri waterway in Arunachal Pradesh. 
Kasowal Bridge: It is over Ravi waterway.

It associates Kasowal territory in Punjab along the India - Pakistan line to the remainder of the country. 

Darbuk-Shyok-Daulat Beg Oldie Road: It associates Leh by means of the towns of Darbuk and Shyok at southern Shyok River Valley, with the Daulat Beg Oldi (DBO) post close to the northern boundary. 

Barsi Bridge (longest extension on Manali–Leh interstate): It is based on Bagga stream, which gets together with Chandra waterway at Tandy in Lahaul to stream down into Jammu and Kashmir as the Chenab.

Ct Value: Covid-19 Test

Ct Value: Covid-19 Test

The ICMR (Indian Council of clinical Research) has chosen a solitary Ct esteem cut-off for deciding if a patient is positive for Covid-19. 

Ct is a worth that arises during RT-PCR tests. All patients with a Ct esteem under 35 might be considered as sure while those with a Ct esteem over 35 might be considered as negative. 

Main key points 

RT-PCR Tests

In a RT-PCR (Reverse Transcription Polymerase Chain Reaction) test, RNA (Ribonucleic corrosive) is extricated from the swab gathered from the patient. It is then changed over into DNA (Deoxyribonucleic corrosive), which is then intensified. 

Intensification alludes to the way toward making various duplicates of the hereditary material - for this situation, DNA. 

This improves the capacity of the test to identify the presence of the infection. 

Intensification happens through a progression of cycles—one duplicate becomes two, two gets four, etc—and it is after various cycles that a perceptible measure of infection is delivered. 

Ct Value

Ct is short for 'Cycle Threshold'. 
The Ct esteem alludes to the quantity of cycles after which the infection can be recognized. 
On the off chance that a higher number of cycles is required, it suggests that the infection went undetected when the quantity of cycles was lower. 

The lower the Ct esteem, the higher the viral burden on the grounds that the infection has been spotted after less cycles. 

It has been made that the time since the beginning of side effects has a more grounded relationship with Ct esteems when contrasted with the seriousness of the illness

Viral Load

It alludes to the measure of hereditary material, generally RNA, of an infection present in a contaminated individual's blood. 

This is communicated as the absolute number of viral particles present in every millilitre of blood. 

A higher viral burden in the blood implies that the infection is recreating and the disease is advancing. 

A contaminated individual with a high popular burden is bound to shed more infection particles, in the process known as "viral shedding".

Oxygen Crisis: Covid-19

Oxygen Crisis: Covid-19

The Liquid Medical Oxygen (LMO) emergency during the second influx of Covid flood has been accelerated by a lack of big haulers and the overwhelming coordination’s of transportation from distance locations. 

Main key points 
Liquid Medical Oxygen-
It is high virtue oxygen appropriate for use in the human body. Along these lines, it is utilized for clinical medicines. 

This oxygen gives a premise to for all intents and purposes all cutting edge sedative strategies, re-establishes tissue oxygen pressure by expanding the oxygen accessibility, helps cardiovascular solidness, and so on 
The World Health Organization remembers this for their List of Essential Medicines. 

As per the Drug Prices Control Order, 2013, LMO is set under the National List of Essential Medicines (NLEM). 

LMO Production in India: 

India has an every day creation limit of at any rate 7,100 Metric Tons (MT) of oxygen, including for mechanical use. 

Because of the emergency, the creation has been expanded to 8,922 MT. What's more, roughly every day deal is 7,017 MT. 

The home-grown creation is relied upon to cross 9,250 MT each day before the finish of April 2021. 

In this manner, India seems, by all accounts, to be creating adequate oxygen to meet the current need. 

Reasons behind the Crisis: 

Distance of Production Plants: 

The greater part of the LMO plants are situated in the east, prompting long transportation pulls and a turnaround season of at any rate 6-7 days for every big hauler. Add to this the issue of states holding up big haulers in transit. 

Limited Tankers: 
As of now, India has 1,224 LMO big haulers with an aggregate limit of 16,732 MT of LMO. This is horribly insufficient in light of the fact that at some random point, there are just 200 big haulers on the way to satisfy a need of 3,500-4,000 MT. 

Organizations not Buying Cryogenic Tankers

Cryogenic big haulers cost around Rs. 50 lakh each. Organizations are not accepting these big haulers in light of the fact that once this wave is finished, that venture will transform into misfortunes. 

Cryogenic Tankers: These are big haulers which store clinical oxygen at - 180 degrees C, have twofold skin vacuum-protected holders, including an inward vessel made of tempered steel. 
Leakage and Irrational Use

Before, the Health Ministry over and over requested clinics to decrease wastage and superfluous oxygen use in Hospitals. Modern specialists additionally raised worries over potential spillages in clinic pipelines that supply oxygen. 

Dark showcasing of oxygen chambers is another issue. 

Government Initiatives: 
Oxygen Express: 

Trains to ship LMO and oxygen chambers the nation over have been begun to battle the progressing emergency. 

Debacle Management Act 2005

The Ministry of Home Affairs summoned Disaster Management Act, 2005 (DM Act) and requested free between state development of oxygen conveying vehicles. 

Restarting Plants: 

The public authority is restarting many shut plants to build the stockpile of LMO, for instance, Sterlite plant in Tamil Nadu will be returned for a very long time to give oxygen supply. 

Utilization of Air Force: 

To accelerate the transportation, Indian Air Force (IAF) is carrying void oxygen big haulers and taking them to modern units that have changed to delivering clinical evaluation oxygen. 

Oxygen Enrichment Unit (OEU): 

It is created by researchers of Council of Scientific and Industrial Research-National Chemical Laboratory (CSIR-NCL), and will help lessen the prerequisite of ventilators and oxygen chambers in homecare, towns and far off places. 

Oxygen enhancement units have extraordinary importance taking into account the Covid-19 pandemic. Patient recuperation can be quicker with supplemental oxygen in beginning phases.

India- Japan relation in time of pandemic

India- Japan relation in time of pandemic – 

According to the recent news the Prime Minister in a telephonic discussion with his Japanese partner talked about different issues including high innovation, ability improvement and fighting with the Covid-19 pandemic together. 

Main key points 
About: 

On Covid-19 pandemic Situation: 
Featured the significance of close India-Japan collaboration to beat difficulties presented by the pandemic, for example, by cooperating to make tough, broadened and dependable inventory chains, guaranteeing solid stockpile of basic materials and innovations, and growing new organizations in assembling and ability improvement. 
In this unique circumstance, the two chiefs stressed the requirement for early operationalization of the Specified Skilled labourers’ (SSW) arrangement to synergize their qualities and accomplish commonly helpful results. 

They likewise featured the Mumbai-Ahmedabad High Speed Rail (MAHSR) project as a brilliant illustration of their participation. 

On Cooperation for Indo-Pacific: 
Affirmed the significance of Japan-India respective and multilateral participation, including Japan-Australia-India-US quadrilateral collaboration, towards understanding a free and open Indo-Pacific. 

On Possible Cooperation in Various fields: 
Like 5G, submarine links, fortifying of modern intensity, broadening of supply chains and improvement projects in the north-eastern state. 

Other Recent Developments Between India and Japan: 
As of late, India, Japan and Australia have officially dispatched the Supply Chain Resilience Initiative (SCRI) in a transition to counter China's strength of the store network in the Indo-Pacific locale. 

The SCRI means to make a righteous pattern of upgrading production network flexibility so as to at last achieving solid, manageable, adjusted and comprehensive development around there. 

Japan has concluded advances and an award totalling around 233 billion yen for a few key framework projects in India, incorporating for a task in the Andaman and Nicobar islands. 

In 2020, India and Japan consented to a coordination’s arrangement that will permit military of the two sides to organize intently in administrations and supplies. The arrangement is known as the Acquisition and Cross-Servicing Agreement (ACSA). 

In 2014, India and Japan overhauled their relationship to 'Extraordinary Strategic and Global Partnership'. 

The India-Japan Comprehensive Economic Partnership Agreement (CEPA) that came into power in August 2011 covers exchange products, administrations, development of regular people, speculations, Intellectual Property Rights, custom methods and other exchange related issues. 

The defence Exercises

India and Japan safeguard powers coordinate a progression of two-sided practices specifically, JIMEX (maritime), SHINYUU Maitri (Air Force), and Dharma Guardian (Army). The two nations likewise take part in Malabar work out (Naval Exercise) with the USA. 

Forward planning 
More coordinated effort and collaboration can demonstrate gainful to the two countries, since India needs complex innovation from Japan. 
There is a gigantic potential as for Make in India. Joint endeavours could be made by blending Japanese computerized innovation with Indian crude materials and work. 

Close participation is the best measure to battle China's developing job in Asia and Indo-Pacific, in physical just as advanced space.

Antimicrobial Resistance: Threat to Global Health Security

Antimicrobial Resistance: Threat to Global Health Security

Antimicrobial obstruction (AMR) is a developing worldwide issue to which the continuous Covid-19 pandemic may additionally contribute. 

With assets conveyed away from antimicrobial stewardship, proof of generous pre-emptive anti-infection use in Covid-19 patients and by implication, with crumbling financial conditions fuelling destitution conceivably affecting on degrees of opposition, AMR danger stays huge. 

Main key points 

Antimicrobial Resistance (Meaning): 

Antimicrobial obstruction is the opposition procured by any microorganism (microbes, infections, organisms, parasite, and so on) against antimicrobial medications (like anti-toxins, antifungals, antivirals, antimalarials, and anthelmintics) that are utilized to treat contaminations. 

Accordingly, standard medicines become inadequate, contaminations endure and may spread to other people. 

Microorganisms that create antimicrobial obstruction are now and then alluded to as "superbugs". 

Basis of Antimicrobial Resistance: 

A few microscopic organisms because of the presence of obstruction qualities are naturally safe and accordingly get by on being presented to anti-infection agents. 

Microorganisms can likewise obtain opposition. This can occur twoly: 

By sharing and moving obstruction qualities present in the remainder of the populace, or 
By hereditary changes that assist the microscopic organisms with enduring anti-infection openness. 

Purposes behind Spread of Antimicrobial Resistance: 

The abuse of antimicrobials in medication and improper use in farming. 

Tainting around drug fabricating destinations where untreated waste deliveries a lot of dynamic antimicrobials into the climate. 

Concerns: 

AMR is now liable for up to 7,00,000 passing’s every year. 

A danger to anticipation and therapy of diseases - operations like organ transplantation, malignancy chemotherapy, diabetes the board and significant medical procedure (for instance, cesarean areas or hip substitutions) become unsafe. 

Builds the expense of medical services with lengthier stays in clinics, extra tests and utilization of more costly medications. 

It is putting the increases of the Millennium Development Goals in danger and jeopardizes accomplishment of the Sustainable Development Goals. 

No new classes of anti-infection agents have made it to the market over the most recent thirty years, to a great extent by virtue of lacking motivating forces for their turn of events and creation. 

Without dire activity, we are making a beeline for anti-toxin end of the world – a future without anti-toxins, with microbes getting totally impervious to treatment and when regular contaminations and minor wounds could by and by execute. 

AMR in India: 

India, with its blend of huge populace, rising wages that work with acquisition of anti-microbials, high weight of irresistible infections and simple over-the-counter admittance to anti-toxins, is a significant locus for the age of obstruction qualities. 

The multi-drug obstruction determinant, New Delhi Metallo-beta-lactamase-1 (NDM-1), arose out of this locale to spread internationally. 

Africa, Europe and different pieces of Asia have additionally been influenced by multi-drug safe typhoid starting from South Asia. 

In India, more than 56,000 infant passings every year because of sepsis are brought about by organic entities that are impervious to initially line anti-toxins. 

India has embraced numerous exercises like Mission Indradhanush — to address low inoculation inclusion — reinforced miniature arranging and extra systems to improve observing and responsibility. 
The Ministry of Health and Family Welfare (MoHFW) distinguished AMR as one of the best 10 needs for the service's collective work with the World Health Organization (WHO). 

India has likewise dispatched the National Action Plan on AMR opposition 2017-2021. 

Forward planning 

Since microorganisms will unavoidably proceed to develop and get safe even to new antimicrobials, we need supported speculations and worldwide coordination to identify and battle new safe strains on a progressing premise. 

Endeavours to control solution of antimicrobials ought to be joined by endeavours to instruct buyers to lessen unseemly interest, issue standard treatment rules that would enable suppliers to confront such requests, just as give point-of-care diagnostics to help clinical dynamic. 

As well as growing new antimicrobials, contamination control measures can lessen anti-microbial use. It is basic to guarantee that each one of the individuals who need an antimicrobial approach it. 
To follow the spread of obstruction in microorganisms, reconnaissance measures to recognize these life forms need to extend past clinics and envelop animals, wastewater and homestead run-offs.